Batiste's Collies

Collie Eye Information

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All of my past litters from Cory, Brandon and Byron have tested normal. CERF Verification site: http://www.vmdb.org/verify.html

 
CEA OR Collie Eye Anomaly

About 95% of collies have some form of CEA. This eye exam can only be given by a Certified Canine Ophthalmologist. CEA or Collie Eye Anomaly is thought to be inherited by an autosomal recessive gene.
 
A recessive trait means there are three types of dogs: unaffected dogs that do not display the trait NOR have genes for the trait; carriers that do not display the trait, but DO have one of the genes for the trait; and affected dogs that have the trait and can only pass along genes for the trait. If a dog is "mildly affected", it is an affected dog and will always pass along CEA to it's puppies. So breeding two "mildly affected" dogs will never result in unaffected, or even carrier puppies. Breeding two apparently normal dogs may result in puppies with CEA if both dogs turn out to be carriers. If a dog ever produces a puppy with CEA, then that dog must be either a carrier or an affected dog itself.
 
An affected dog is one who, upon dilation of the eye, shows a visible deviation from a normal or unaffected eye when viewed with the proper instruments. To be affected a dog would have inherited an affected gene from both parents.
 
A normal eyed dog is a dog who, when examined by a veterinary ophthalmologist shows no visible signs of CEA, but possesses only one normal gene; the other gene is affected.
 
A non-carrier is a normal eyed collie who carries no affected genes. He cannot produce anything but normal eyed collies
 
A non-carrier cannot be diagnosed by an eye check, as we are dealing with genes not effects of genes. If a dog comes from two non-carrier parents, he is a non-carrier. Whether or not a dog is a non-carrier can only be defined by breeding. If a dog produces a significant number of puppies, bred to an affected or normal eyed stud or bitch, and all have normal eyes, no matter what the eye check of the other parent is, it's a safe bet he/she is a non-carrier.

Progressive Retinal Atrophy

PRA will result in blindness. A well known and widely used stud dog in the '70s was found to be a carrier and did produce blind puppies. While the breeder now test-breeds all their stock available for stud services, PRA is present in a number of lines. Most reputable breeders who know or suspect that PRA is in their lines do test-breed. Since PRA in Collies is a simple recessive, it has been easier to control than CEA.

ALL reputable breeders should eye check not
only their breeding stock, but all
puppies that are offered for sale
.

Expected Results of Breeding Strategies for Inherited Recessive Diseases

Parent 2     Genotype

Normal

Carrier

Affected

All = Normal

1/2 = Normal
1/2 = Carriers

All = Carriers

1/2 = Normal
1/2 = Carriers

1/4 = Normal
1/2 = Carriers
1/4 = Affected

1/2 = Carriers
1/2 = Affected

All = Carriers

1/2 = Carriers
1/2 = Affected

All = Affected

The table shows the desirable breedings (gray-shaded boxes) which have at least one parent that is Normal by the OptiGen CEA/CH test. All other breedings are at risk of producing pups affected with CEA/CH.

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